PreTect HPV-Proofer is an assay for the qualitative detection of the presence of Human Papillomavirus, HPV, E6/E7 oncogene mRNA from carcinogenic HPV types 16, 18, 31, 33, 45.
PreTect HPV-Proofer is therefore a valuable tool to identify women with high risk of severe dysplasia.
This way the assay reduces unnecessary referral costs, and also psychological stress for the women concerned.
Risk stratification and direct genotyping
E6/E7 mRNA expression from HPV 16, 18, 31, 33 and 45
Identifies cervical precursors most likely to progress to invasive cancers
Accurate patient management; Triaging HPV DNA positive women/Cytology
Enhances identification of cervical adenocarcinoma
Minimise unnecessary referral and over-treatment
Suitable even in young women
|Individual HPV||E6/E7 mRNA HPV 16, 18, 31, 33 and 45|
|Intrinsic Sample||Targeting mRNA from housekeeping gene|
|Sample type:||Cervical samples|
|Preservatives:||PreTect TM (PreTect AS); PreservCyt; SurePath|
|Input-material:||Isolated Nucleic Acid (DNA/RNA)*|
|Technology:||Real time NASBA|
|Isothermal amplification (41°C)|
|Six specific molecular beacons|
|Format:||96-well PCR plate/strips Pre-filled with reagents|
|Assay time:||~ 150 minutes|
|Instrumentation:||Fluorescence reader /|
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